Coronasomnia is a not-so-surprising side-effect of the global pandemic. More and more of us are having trouble falling asleep. We wanted to find a way to get inside that nighttime world, to see why people are awake and what they are thinking about. So what’d Radiolab decide to do? Open up the phone lines and talk to you. We created an insomnia hotline and on this week’s experimental episode, we stayed up all night, taking hundreds of calls, spilling secrets, and at long last, watching the sunrise peek through. This episode was produced by Lulu Miller with Rachael Cusick, Tracie Hunte, Tobin Low, Sarah Qari, Molly Webster, Pat Walters, Shima Oliaee, and Jonny Moens. Want more Radiolab in your life? Sign up for our newsletter! We share our latest favorites: articles, tv shows, funny Youtube videos, chocolate chip cookie recipes, and more. Support Radiolab by becoming a member today at Radiolab.org/donate.
We lost a legend. Supreme Court Justice Ruth Bader Ginsburg died on September 18th, 2020. She was 87. In honor of her passing we are re-airing the More Perfect episode dedicated to one of her cases, because it offers a unique portrait of how one person can make change in the world. This is the story of how Ginsburg, as a young lawyer at the ACLU, convinced an all-male Supreme Court to take discrimination against women seriously - using a case on discrimination against men. This episode was reported by Julia Longoria. Special thanks to Stephen Wiesenfeld, Alison Keith, and Bob Darcy. Supreme Court archival audio comes from Oyez®, a free law project in collaboration with the Legal Information Institute at Cornell. Support Radiolab today at Radiolab.org/donate.
There are so many ways to fall—in love, asleep, even flat on your face. This hour, Radiolab dives into stories of great falls. We jump into a black hole, take a trip over Niagara Falls, upend some myths about falling cats, and plunge into our favorite songs about falling. Support Radiolab by becoming a member today at Radiolab.org/donate.
Today, we return to the lab of neuroscientist Li-Huei Tsai, which brought us one of our favorite stories from four years ago - about the power of flashing lights on an Alzheimer’s-addled (mouse) brain. In this update, Li-Huei tells us about her team’s latest research, which now includes flashing sound, and ways in which light and sound together might retrieve lost memories. This new science is not a cure, and is far from a treatment, but it’s a finding so … simple, you won’t be able to shake it. Come join us for a lab visit, where we’ll meet some mice, stare at some light, and come face-to-face with the mystery of memory. We can promise you: by the end, you’ll never think the same way about Christmas lights again. Or jingle bells. This update was reported by Molly Webster, and produced by Rachael Cusick. The original episode was produced by Annie McEwen, Matt Kielty, and Molly Webster, with help from Simon Adler. Special thanks to Ed Boyden, Cognito Therapeutics, Brad Dickerson, Karen Duff, Zaven Khachaturian, Michael Lutz, Kevin M. Spencer, and Peter Uhlhaas. Support Radiolab by becoming a member today at Radiolab.org/donate. Molly's note about the image: Those neon green things in the image are microglia, the brain’s immune cells, or, as we describe them in our episode, the janitor cells of the brain. Straight from MIT’s research files, this image shows microglia who have gotten light stimulation therapy (one can only hope in the flicker room). You can see their many, super-long tentacles, which would be used to feel out anything that didn’t belong in the brain. And then they’d eat it! Further reading: Li-Huei and co’s gamma sound and light paper: Multi-sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition
Six years ago, a new infection began popping up in four different hospitals on three different continents, all around the same time. It wasn’t a bacteria, or a virus. It was ... a killer fungus. No one knew where it came from, or why. Today, the story of an ancient showdown between fungus and mammals that started when dinosaurs disappeared from the earth. Back then, the battle swung in our favor (spoiler alert!) and we’ve been hanging onto that win ever since. But one scientist suggests that the rise of this new infectious fungus indicates our edge is slipping, degree by increasing degree. This episode was reported by Molly Webster, and produced by Molly and Bethel Habte, with production help from Tad Davis. Special thanks to Julie Parsonnet and Aviv Bergman. Support Radiolab today at Radiolab.org/donate. Further Fungus Reading: NYTimes feature on the mysterious rise of Candida auris. Arturo's paper: “On the emergence of Candida auris, Climate Change, Azoles, Swamps, and Birds”, by Arturo Casadevall, et al. “On the Origins of a Species: What Might Explain the Rise of Candida auris?”, a report from the CDC.