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You are listening to the Darina lead show. I'm Daryn. I've spent the last 15 years exploring the planet, looking for healthy foods, superfoods, environmental solutions, and I've had my mind blown along the way by the people, the far off places I have been and the life altering events that have changed my life forever. My goal is to help you dive deep into some of the issues of our modern day life, society's fatal conveniences, the things that we do that we're indoctrinated into thinking we have to, even though those things are negatively affecting us and in some cases slowly destroying us and even killing us every week.

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I have honest conversations with people that inspire me. My hope is, through their knowledge and unique perspectives, they'll inspire you two together. We'll explore how you can make small tweaks in your life that amount to big changes for you, the people around you and the planet. So let's do this. This is my show, the Darian Lehnsherr. What's up, everybody? How's it going? Welcome back to the show. Still for another episode, stoked to have you join and give me some of your time today, because it's a great episode.

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But I just wanted to say I'm grateful for all of you. I'm grateful for all of the new subscribers to make sure you subscribe because we're on a mission, people. We are definitely on a mission. I'm mobilizing. I'm listening. I'm creating things that are going to create a super life program moving forward, a super life ambassador program, more specifically, super life warriors, so that you can stay healthy, fit, eternally awesome, and then turn that awesomeness into being an eco warrior as you become more aware of our current climate and as we feed you more information with the collaborations, the people that we're gathering and talking to and the research that I'm doing with some people, we're stoked.

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So I've listened to you from the Down to Earth show. I've listened to all the messages receiving thousands of messages every day of people being inspired, people being touched, people wanting to do something with their lives. And we are putting that together. So stay tuned for that. We've got Dr. Alex Posto, his long name, Poggio Topolice. Right. Dr. Alex Paisios, helpless. Say that ten times fast and you've accomplished something today. We had an incredible conversation.

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There's so many synergies here. He runs the Policy Institute. And, you know, we talk to longevity. We talked superfoods. We talked about background that he has from being a Shalan trained warrior, as well as having his medical degree. We shared in that kind of education of people and plant based diet. And it perfectly meshes with his optimization, his his is research and his ongoing orientation around microbiome and restoration. So anyway, I hope you enjoy the show.

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This was of great fun and this guy is doing incredible stuff. So stay tuned and enjoy the show. Cool, so, hey, man, welcome, super excited to talk to you, Dr. Pozzo, I mean, you've got it. You've got to give me the first benefit of the doubt and pronounce your last name for me. Pozzo topolice, Pazira topolice.

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See, it flows. It definitely wasn't going to flow if I tried it. So I'm glad I'm glad you set the tone. So thank you for jumping on here. And just again, getting to kind of see your bio functional medicine, antiaging kind of regenerative aging. And then there's some interesting terms that you have kind of thrown in the mix around medical engineering, which is pretty cool. And I think we have some actually.

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I saw your residency was finished up at Mercer University, so I'm going to open up something around that that is going to go where we might have a connection.

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So anyway, so I'm going to give everyone heard your intro in the beginning, but just give a little give a little synopsis of you because you have this medical degree. But then you just went all the way in on regenerative healing and functional medicine. And I'd love just to hear that story a bit. Sure.

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I mean, backing up probably into like undergrad years. I was an environmental science and I was physical anthropology. So while I was really excited that you've done some traveling around the Amazon, so I studied squareness at this joffre or tamarin monkeys in Panama or how that was like my first experience really with the wild and seeing animals in the wild and just seeing how the ecosystem works.

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And it really spurred a lot in me to go into science and then just fascination with primates. And obviously we're primates.

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So that laid the foundation for that. Later, I went to University of Colorado and did some neuroscience work and some biochemistry. That was after I had found yoga and shaman martial arts kung fu. And before I went to medical school, I was really deep into teaching yoga and doing Ashtanga yoga and becoming a black belt and kung fu.

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And I found that doing this, those simple practices and becoming vegan at that time.

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I adhere to all kinds of injuries in myself. I used to be a pole vaulter and, you know, my shoulders were all shot from that.

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And so it was just great to see how I could get my body back and just the level of clarity and just how good it felt to eat plants. And so then I'm like, OK, I want to take this to the next level and I want to go to medical school.

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And while I was in medical school, I was like, well, there's all these other doctors that are doing things outside of just Western medicine's doing. So I got involved in the American Academy into Aging Medicine and their fellowship program and then later did a stem cell fellowship with them. And recently I just did a peptide certification with them. So just putting that all together was great. And my residency program was one of the few programs that did integrative medicine in residency through the University of Arizona, through Dr.

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Weil. So I got a really great background in stuff like that.

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And then what I try to do is when I started putting everything together, I was like, wow, there's so many moving parts and you're trying to treat somebody, but you don't want to overwhelm them.

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And there's so many different components from their behaviors, right, to their diets to supplements, you're going to give them to the medications are going to do with testing. You're going to do. So just what do we do? And I look to engineers and I happen to have a lot of really great friends that are engineers and they're like, oh, engineers solve all those problems all the time.

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What are you talking about? That's not typical that systems based engineering and mechanical engineering, maintenance, engineering. So I'm like, well, I'm not an engineer, but I started looking into it and I was like, why are physicians engineers?

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I'm like, we should have education in engineering.

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Right? Because if you're going to optimize a system, well, you need to do systems based engineering or you need to do maintenance, engineering. And these protocols are already set. And that's why airplanes don't fall to the sky.

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And that's why Formula One cars are as amazing as they are. And, you know, you can just see so many examples from like the software industry to everywhere Google. Everyone is using systems based engineering. It's just standard except for massive. Well, certainly the normal the normal medicine of the kind of the the the germ theory approach of the American Medical Association, you catch this, you get this, and then we we deal with that down the road.

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But before you get into that, I am ABB's I just have to highlight there's so many things that you just said that I want to unpack. And one is when I was seven years old, my dad asked me what I wanted to do. I said, I want to go to Shalin and study. And that was a small town kid from Minnesota, so clearly that didn't happen, but my dad enrolled me in an adult karate class and I was so eager, I just annoyed that the instructor and he kicked me out.

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But the medical engineering man that just that just hit me. So square on it. Of course, there's there's Microsystems, there's macro systems, and then we have our ecosystem. And, of course, we need to optimize it. Yeah.

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And we need to track it. You know, it's like electronic medical records are not very good for tracking optimization.

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They're really good for, like tracking problems and putting notes in and ordering prescriptions. But it's not really good for optimization. But project management really is. And there's so many great project management suites out there. And if you enter a patient into a project management suite as a project, well, then you can say, OK, we're checking in on these things at these intervals. Right. And we're seeing if they're compliant with their supplements at these times. And I'm ordering labs at these intervals.

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Right. And then they start on this exercise and then once they're done with that and they progressed to the next exercise so they don't get overwhelmed. And so and we're just in the very beginning, I'm calling this one point, even though it's far greater than anything that we've done before, it's still a very beginning.

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And what I'm hoping is going to happen is once we start getting this out is that I want other doctors to do it. I don't want this to just be some proprietary thing that you have to come to the Passu Institute for. I want to see all types of people using different types of engineering to optimize individuals. And then we can talk together and we can say, OK, what's the best way to go about this? Because it's never really been done.

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So let's take it through so I can and people can understand, like if I were to come to you, what would be the protocol of kind of this concierge approach of of and also how you can expand that and what you're talking about, like how would you approach a client and and using all of these principles of functional and diagnostics and medical engineering?

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Sure. It's a great question. So the first thing we do is we have patients fill out a questionnaire. And the other thing that we do is we have them send in all their old medical records that they can get their hands on. We also get them out to see if they have the amount of funds that are needed to do a program. And we do that early on because we don't want to disappoint somebody and say, OK, we can do this fantastic program for you, but you don't have the money for it.

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So it just kind of see, we let them out to see what kind of expendable income they have to put towards this and what they're willing to put towards it because they don't really change the plan quite a bit. There's different levels that you can go to for optimization. So after we kind of let them out and they fill the questionnaire out and they send in their medical info, I go through all that and then we do about an hour to an hour and a half consultation in person or now mostly because after I get all that kind of information on them, I get their background and feel them out.

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The one thing I can really get an idea of, if you look into maintenance, engineering or systems based engineering, there's this thing called the discovery process. And in the discovery process, when you're looking at a new system, you want to find out what are the major problems that you're experiencing right now that could lead to catastrophic events. And we treat those right away because you don't want there's a crack in the fuselage, an airplane, who cared about the seats.

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Right, right.

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So some of your diagnostics to uncover some of that beyond the person just saying, what are some of those things that you use to uncover some of them so that a lot of that's in the second process.

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So the first process is kind of just see, like, OK, family history. What are you complaining about? What's been going on? That gives me an idea of what basic labs I need to get in on. My basic labs are not basic, but it's just mostly blood work. And then we get that back and actually where they're at. And then I create a plan. And that plan is all of these other diagnostics that we need in common diagnostics that I'll get our calcium scores and lots of ultrasound on different parts of the vascular system.

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And two of the things that kill us in today's society, especially here in the states, are strokes, heart attacks and cancer. So those are catastrophic things that we need to focus on right away. And there's plenty of men that die in their 40s that are in fantastic shape. Right. To have excellent aerobic capacity. They can. They can. They're really strong. They look fit. They look good. But you can't tell what's going on with their vascular system.

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So between the calcium scores, between the ultrasound and then we do a lot of metabolic testing so we can see how good the endothelial function is. And when I talk to patients about endothelium, a lot of times are like, well, what is endothelium like? It's the largest organ of your body. It's the lining of every blood vessel. It's that it's the network of your whole body, the infrastructure. So without quality endothelium, you can't supply organs with oxygen, nutrients.

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You can't get rid of waste. Right. You can't dilate artery arterials. So why focus on that a lot? Because with quality endothelium, a lot of things just kind of go away and then we get epigenetic cancer testing. So, you know, which is really new test so we can see what the major cancers. Is there a cancer burden in the body that you're that you're currently fighting? And these tests allow us to see the progression of cancer before you can ever pick it up with a scan and then you can just use it.

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You can use all these other modalities that we have, even from stress reduction supplements, IVs, to start working on the immune system and see if we can get those scores down. So it never really actually progresses to cancer.

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So that epigenetic cancer thing you're looking at to just try to simplify it for people, it's like those are the things that in a lifestyle people are either not doing or doing or doing that's causing them.

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Sure. And mostly it's stress. Right. And when I come to match it and say it's not about the external stress. Right. External stress is good for you. The external stress of lifting something heavy makes you strong. It's a stress, the external stress and holding your horse stance and holding your breath. It's hard, but it makes you stronger, right?

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So the stressors that we get in life there, they could possibly make it stronger by making us adapt well to what's happening. But when you turn it inward and you affect your breathing and most people, that affects your pelvic floor. And that's like a whole new thing that we've been exploring is pelvic floor therapy and tension as it affects the vagus nerve and then shuts your immune system off, affects your breathing rate. So there's so many things involved with just the basics.

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Unpack that a little bit, because I also believe that that's extremely important. I've been doing pelvic stabilization for a couple of years now and I learned it from a Ph.D. from Coyte in in kinesiology, and she was all about that. And she also studied from some ancient indigenous people in Peru. So it was like this melding it and that stability. And I didn't realize about the vagus nerve. I was just because I have a thirty year college football injury in my lower back and nothing stabilize that more than doing pelvic stabilization and proper breathing techniques, diaphragmatic, deep breathing, all of the stuff.

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So so what do you find then with pelvic instability? Like what are the pleura freighted causal things that are what you're seeing as a result of that instability?

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So two different things. There's a pelvic instability. Right. And that has to do with the way that your pelvis is connected to the. To your body. Some people call it core, but it's a lot more involved than that. And then there's just the muscles of the pelvic floor from your pubic bone to your tailbone.

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And what happens with people with a lot of high stress in their life is that tone of those muscles becomes very high, which makes sense, because if you see an animal that might be a threat to you when you're a primitive human, well, you're going to constrict your pelvic floor because you can't go to the bathroom. You have to get the hell out of there. You have to fight. And that constriction of the pelvic floor, what it does is it pulls the tailbone under a little bit and anus tighten up and the muscles around the urethra tighten up.

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And then that sends a signal up the vagus nerve, like stop digestion, stop the immune system, stop all unnecessary organs, increase the speed of processing in the brain, which if you're not running from something, you know, you're going to you're going to start spinning, your stress is going to get worse and breathing heart rate and muscles. So fantastic if you actually have to do something. Not so great if it's all day, every day. Right.

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And that's that's what we're really seeing, the modern day fatality of our kind of overall stress now more than ever with this pandemic and this this situation and that situation. And we're just if we can't kind of unload that stress, then at the core we're dealing with this with this deep stress that's just sending it out to the alarm system and the domino effect. And and people really don't understand that. Oh, I just got to be less stress. Right.

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But it's so right. And it's it's so deep and they don't know, you know, it's like I've been around people doing meditation, yoga and come forward until I got into this medicine. There wasn't really an objective way to tell whether or not is your meditation effective? Is your yoga effective? Is your tai chi effective? And now we have biofeedback and we have neurofeedback. And so they can see, you know, there's a thing called beat to beat variability.

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So as your heart beats and you feel your pulse, it feels like it's a metronome, but it's not. If you're at rest and you're calm, every beat is off by a couple of milliseconds. So that's good beat to beat variability. That means that you're at rest and your body's functioning properly. When it starts beating perfectly like a metronome, you're stressed out. And if you're not doing a proper meditation, it's going to be revealed in that.

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And so we can hook you up to these devices. And there's even home devices for the listeners that can go to heart math dog that or you're done that and you can get these devices and you can learn how to do the training so that you can increase your beat to beat variability by doing breathing exercises and focusing. And they call that this thing called coherence and really improve yourself. And from a neurological standpoint, you can do quantitative electroencephalogram and you can see what's going on in the brain and the different portions of the brain.

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Are they in coherence or something really hot or something really cold? And then you can sit in front of a computer screen and train those parts of the brain to get into coherence or to say somebody with ADHD to turn on that prefrontal cortex. So just they both go together. But now you can see my successful at my practice and how do I make my practice better?

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And that's huge what you just said, because it's also like the average person any person wants to know what they're doing is going to improve them. And you can hear all the stuff like I should meditate, dammit, I should meditate, dammit, I should. But especially now I'm stressed because of this and that and finances and whatever. But if you can actually have some some quantifiable things that you can understand about, OK, back to your great terminology, which is medical engineering.

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If I have this thing that I can understand and then do and it gives me pragmatic results towards this very thing that I need to balance in my life. Now, that's something that's extremely important because you can grab any meditation app. There's a zillion out at this point, but it's actually creating effectiveness for your wellbeing. Right. And that's that's absolutely. And I'm not against meditation. I like meditation from the schools of thought, from the yoga that I've been exposed to in the kung fu I've been exposed to.

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Meditation is an advanced practice. And until you've really learned how to control the breath, control the pelvic floor, give good attention to things, to be aware of your course of your body and the tension within it. Controlling where your eyes are gazing and it's under your conscious control, you don't really have business to do meditation, because without all that self-control and awareness, you might just feed the ego and you might stimulate the mind to get more control over you rather than you getting control over it.

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So just there's there's always caveats to everything. Right. And I think that things need to be progressive and how you go about it with someone.

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So if someone comes to you and through this diagnostics, what goes on from there? And so you're you're looking at them from all of these different approaches. You've done the blood tests. You've looked at their history. From what you've seen, what do you take them from there?

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So from there, then we create a plan for them. And right now we're using a spreadsheet to show them all on one page of what's going on. They don't have to, like, really zero in on all the details because in the follow up, we're telling them what they need to do next. But the very first thing is, OK, we want you to start to do these movement exercises. I want you to work on this range in motion, because in the in the House, we're looking at their posture and the range of motion, doing a physical exam, trying to work on that.

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Where's their balance at? So all those things are set together so that they can practice at a basic level depending on where they're at. I mean, we have professional athletes come in to show that we don't have to begin at the beginning for them. And everyone is at a different spot. Some people have a fantastic diet. Some people don't even know the importance of plants. So everyone's at a different starting point. And then we get into all the medicine.

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And so it's their supplements and there's pharmaceuticals and some people come in and they're all about supplements and that's fine and they don't want any pharmaceuticals. And so you have to educate them that not all pharmaceuticals are bad and there's plenty of pharmaceuticals that we need to get rid of synthetic cells. And to put in the word that most people understand is biohacking, which is turn on certain genes so that we can live better and have less cancer. And some of the medicines that we use a lot for stuff like that are low dose naltrexone that form an even tiny bit of aspirin, less than a baby aspirin.

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We use angiotensin receptor blockers like Mercado's to modulate a gene called Dragana. And then we use Analytica drugs that are some of them are giving chemotherapy drugs like that then and then some of them are just phytonutrient, like quercetin or visits. So it's a whole combination of stuff. And we even use lots of peptides so that people can turn on different things like body protection, complex one fifty seven when they're injured or they have an autoimmune disease, their gut or CJC twelve ninety five and ephemerality, so that we can raise growth hormone in bursts so we can get people to get away from their sarcopenia, their loss of muscle mass so they can as they age, they continue to maintain that and the foundation of everything as people age is a hormone replacement and we have over what, twenty seven years now of really good data for hormone replacement done by bioidentical.

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So and I find that if you don't replace your hormones, it's a very, very difficult to maintain health span.

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Now, is that is that mostly focused on women towards menopause? But it is also equally or somewhat close to it. Also men with.

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Oh for sure. It's equally men and women and both men and women. I think the most important hormone is testosterone.

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And you can look at Dr Rebecca Glaeser's work at hormone balance to work with her work with women and testosterone. It's absolutely fantastic. She's had a really fantastic way of lowering their cancers, their breast cancer and breast cancer risk. And it depends, obviously, on the pathology of the breast cancer. But estrogen, breast cancers, they respond very, very well to testosterone. And in many cases, it's better than the chemotherapy regimens and you don't get sick.

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So definitely take a look at that. And we use pellet therapy here in the clinic. I don't really use a lot of injectables and I don't usually use a lot of transdermal. And it's because we get much better to control the testosterone with the small pellets, kind of like a little tic tac and just goes under your skin. We do it every hundred days. Some people are doing pellets, more and more of them over a longer period of time.

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I like doing it over a shorter period of time so you don't get as many peaks and troughs when people in. Act like they're getting a peak and trough every couple of days, and it's more like a drug effect. I think it has more effect on families. Good. But when you give testosterone over a longer period of time and you have steady state, they have much better results and you find that people have less brain fog and they have better self-confidence, they repair quickly from workouts.

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They're able to maintain body mass. And a lot of the studies are showing that they're able to maintain brain mass and which is a huge component in maintaining brain mass over time.

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So for years, maybe all, most of my life, people have been asking me what kind of foods you eat, what kind of exercises do do, what kind of water should I drink, all of these things and so much more we put into a 21 day program. So that can take you through a theme every day of knowledge, action, and then eating this delicious meals, working out, getting support, anchoring in these new habits. So you can do what?

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So that you can kick ass. So you have the energy, the vitality to live the kind of life that you really want. That's what it's all about. So all in this app, we have grocery lists, we have education about real hydration and what greater oxygenation and the balance of organization. All of these things we are diving into as you're heading down this hero's journey of implementation into a new life to give you the kind of life that you actually want.

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So join my tribe. All you have to do is go to one to one tribe, dotcom, sign up and you get three free days. Join me on this hero's journey. Join the tribe. Many of you who follow me know I've spent most of my life searching for the healthiest foods on the planet. If you look hard enough, there are a few unknown, extraordinary foods around the world that people still don't know about. And a few years ago, I came across my favorite superfood discovery of all time verrucas nuts.

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D, A, are I. And I know you will enjoy. I've been involved in some studies and plant based studies where we absolutely and there's plenty that have been published where we got people off of meat, dairy, fish and eggs, men, testosterone in the matter of three weeks went up by 30 percent. So so obviously, you optimizing someone's kind of lifestyle, eating and stressors and stuff like that. So when when would you kind of optimize them in terms of what they're doing?

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And then when would you go, hey, listen, we need to kind of bring in some replacement, like what's your protocol like that with there?

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You just have to look everyone's different when they start to lose things. But before I just start throwing all that testosterone at people, if they're older, if they come in their 50s, of course, I'm just got my testosterone right. And we're going to do everything else at the same time simultaneously. But I see a lot of kids coming in, you know, in their late 20s or early thirties, and they have extremely low testosterone. And I'm talking like in the two hundreds, so I'm not going to give them that.

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But I know that there's something going on in their life that's causing that. So like you said, you know, we try to get them to go plant based and we'll get them to modulate their stress because stress has a huge impact on hormones. And then we started to get them to do the proper kind of exercises and the exercises that we really focus on in the clinic outside of yoga and in some of the exercises that give people are.

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Lifting but lifting for power, not body building, and most of the trainers out there, they're only trained for hypertrophy exercises and it ends up causing a lot of damage to the muscle cells. And you don't get a great strength to weight ratio. I'm a big believer in like Mark Rippetoe and strong people are really hard to kill. So we want to make people strong and sets three sets of five. Basically, it's kind of a strength kind of thing.

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And the deadlifting squats are way up there for us. And we show because we have all the studies that you grow mitochondria and you make more mitochondria by doing that kind of stuff. And it has profound effects on the body.

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And the other thing that I really hard to keep, you got to do a hundred yards, sprints hard as you can. Obviously, you haven't done them in 20 years or something. You've got to work up to it. But the really profound things happen and we go into depth about energy systems and not let the people understand this.

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But like, if you ran a couple of miles, well, you really didn't use up your ATP and you're creating reserves, right, for second to ATP, for second to creating. And it's really hard to tap into those. You have to be at one hundred percent output for those to be depleted. And when you deplete those, then all of a sudden there's all this free adenosine everywhere and your mitochondria freak out and they're like, oh my God, we're ATP deficit.

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We need to make ourselves bigger. We need to divide. We need to become more efficient. And then you have this surplus of energy for the rest of the day. And as you go on in life and your brain needs so much ATP, but it can't work out. And we have all that data from all the PhDs that sit there and do all this work and they're the most likely to get Alzheimer's. And you can go beyond that. Right.

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And that's what the whole engineering program's about, is optimization. So we'll have some top athletes that will come in and then we'll run blood work and we'll run. It's pretty routine for us to look at environmental toxins and to look at heavy metal burden and then to look at how your hormones are being metabolized by your liver. And so we can look at it by looking at those things. You can see like how are these compounds affecting my hormones?

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How are they affecting my immune system? So am I going to get cancer? I'm just not going to feel well, I'm going to feel foggy or my hormones are thrown off and then what is necessary to get them out. So there's all these, like, standard detoxes on the Internet. And I'm not saying that they're terrible, but they're not targeted at the compounds that you're that you're burdened with. So when we do these testing, we can say, OK, this is the way that we're going to eliminate it.

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It's going to be for this amount of time and then recheck and see where you're at. And then we get a much better picture and be able to optimize it. And what we found is that even top athletes get better.

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And and I really like that terminology. I'm going to steal it and give you credit for it, the medical engineering, because I'm always amazed. Then you do something specifically for like call it a heavy metal, call it a parasite, a bacteria. Like if you do it specifically in some of these techniques that's been proven to work, it's amazing what the body will do, what the body will let go of. And but but and I think people need to know that because people need to take proactivity with their bodies and they're running around and we're all being exposed.

[00:38:07]

Unfortunately, our environments got heavy metals. It's got estrogen mimicking compounds. We're compromised, period. We're compromised. Absolutely. So we have to take responsibility and be proactive and connect with doctors like yourself that are looking at the ecosystem testing for the ecosystem and then specializing into how to. Relieve that body of its burden that you may not even be conscious of, you just feel fatigued, broken down or whatever, but it's it's I just want to say I'm amazed at the body because it is so specific when the body goes, oh, I got it.

[00:38:55]

And then boom, it detox in a very specific way. It's incredible. It really is incredible, you know, and then like you're saying, you know, we're talking about food and everything like that and the gut. So many people that are gut microbiome is so far off of optimal. And you can't really tell by like, whether you go to the bathroom every day or constipated, you formed stool. That doesn't really give you the insight that you need.

[00:39:23]

And what I found is even by starting to change the diet, sometimes the bacteria that have been living there for a long time that are not going to go away without a fight, they are embedded in that biofilm.

[00:39:38]

And you getting rid of them, unless you're doing something specific to get rid of them and and and to replenish the microbiome. And hopefully soon the the laws will change. Your fecal transplants will become legal because they're really, really a promising thing. And that would really help a lot of people.

[00:39:59]

And they're doing it outside of the country in certain places because it takes a long time to really build a good microbiome. If you've been plant based for a long time and you've been taking care of yourself. But if you're one of these people that's been eating a pretty carb diet, which is standard American diet and going to restaurants a lot, where you're getting high fatty meals and you're getting the animals mostly from Gitmo and all this kind of stuff, all your terrible gut.

[00:40:29]

And when you start changing, you start adding a lot of fiber. You can have this horrendous bloating and all kinds of problems. And we have to give you enzymes and we give you probiotics. And, you know, I am biome from Dr. Bush and things like that. So it does work. But if we did have microbiome transplant that was legal here, we could fix a lot of these problems in a matter of weeks. That that that stuff to me is astonishing, that it isn't, but it's not surprising because of its just some of the bureaucratic backwardness of some of this stuff.

[00:41:03]

And I said this in my book talking about how incredibly kind of bypassing the mind and that you talking about the strength of they don't want to give up the fight, like sending signals of their cravings. And we think it's our cravings when in fact peptides through peptides like it's like you think you have any control band, you're you're smelling, you know, that fast food. And it's really those microbes that are sending you those insatiable cravings that you barely have any control over.

[00:41:44]

So unless you do a very drastic stoppage to allow the time to convert over, because once you get you've seen this right, once people get over that hump, there is cravings completely changed because ultimately your ecosystem has changed.

[00:42:02]

I have this discussion with patients a lot. I'm like, you go to a forest and it's fall and everything's decaying, everything's dead. You have these leaves decaying on the ground, Styx, all kinds of stuff. I'm like, go pick up that litter layer and smell it. And you like it. It's like, oh, that's the smell of fall. That's wonderful. That's decaying matter. It's all kinds of bacteria. But it smells good to you because those bacteria are beneficial to you.

[00:42:30]

They break down plant matter. They protect you from other microbiome like invading species. They digest things for you. They do all kinds of detox for you. But then you walk further and you find like a dead squirrel and you smell a dead squirrel. And it's not so good because it's affecting bacteria. Why is it so good to you? Because those bacteria won't do anything for you. And when there's nothing more for them to eat, well, they're going to try to digest you and the peptides that the plant based bacteria are going to release make you calm.

[00:43:06]

And the ones that work from eating the animal or they want to make you a little bit more angst, because if you're a little bit more angry kind of a person, well, you're going to go kill something.

[00:43:17]

That's a big, incredible topic to to start to grok and start to understand, because what we just said, what we just talked about, about that peptide strength of those microbiomes. So why wouldn't they also be contributing to your killing nature if if that's what you've been eating? Right. So if if if that purification and those quote unquote, other microbes have been used to the putrefied flesh of another being, then they're definitely going to be calling out for the necessary factors that are involved with them getting more of that purification.

[00:44:09]

Hey, I want to talk about Mercer University and your residence, Mercer was really great for integrative medicine because we had the integrative medicine residency program. So we got most of the stuff that comes out of University of Arizona there, integrated program we were exposed to. So that was good. And, you know, doing a residency is so important for any physician, even if you're just doing functional medicine or, you know, integrative medicine, if you haven't really seen disease in the hospital and you haven't had to be a resident and run your butt off and work crazy hours and see all kinds of stuff, your problem solving is really affected.

[00:44:55]

And I didn't really think that going into residency, I was just like, oh, what do I need this for? Is I really what I want to do, I want to do something else. And I'm not going to really do this primary care and I'm going to do surgery and do this kind of stuff. But doing all those rotations and being exposed to all that and definitely heightened my ability to diagnose and to treat. So and it's one of the reasons that I'm not a really big fan of the future of primary care is working in this country right there, moving primary care to secondary providers and to nurse practitioners.

[00:45:31]

And while they're well educated, there's nothing wrong with their education. They haven't had that, you know, throw you into the mix for three years, you know, and really see all this disease and have to deal with it. And our best physicians should be primary care, not specialists. It's a lot easier to do a specialist job. It's really difficult to diagnose something that might be messed up once you diagnose the specialist. It's a pretty easy job by.

[00:46:02]

But in our country of the top docs, they're going into specialty because that's where the money is. And we're going to really have some terrible things happen to a lot of people because they're not going to miss their diagnosis.

[00:46:14]

That's the I mean, I'm glad you brought that up, because that's that's one of the really big issues we have in our health care system and our normal health care system and the reductionism that gets so myopic and focused and you literally staring at your feet when you're walking through a trail and you don't see the flowers, you don't see the trees, you don't see anything else, and you probably walk off a cliff. And that's kind of our medical system.

[00:46:40]

Like the speciality is you can't see. And that's why I love doctors like yourself. And I mean the first doga to Shalin to integrative to medical engineering to have that approach, but also through the diagnostics and through common sense dealing with people. That's that's how we have to move. And it's very important because we miss I mean, it's just it just makes no sense. But most people are just jumping around from specialist to specialist. And then, of course, it sets you up from a pharmaceutical petri dish of just one drug after another, never getting to any sort of health.

[00:47:29]

Totally, and then the thing that I'm really trying to push people to understand is age reversal medicine. Age reversal medicine has only been here for a couple of years now, but it has the greatest potential to help all of us. And if you look in the summer literature at a university that met the theological foundation, the Book Institute, Orebody Grey, look at some of these things that are going on. That's the future of everything and the people that really need to focus on this the most.

[00:48:00]

If you're 40 years old or above the people that were just born today, that medicine will probably be refined in 40 to 50 years and it'll be applied to them. So they might get older and they get these viruses that can be injected into their body or what other techniques we're going to have. All the cells will die. All their epigenetics will be reset to a young person and they'll be basically immortal. But for all of us, we need to learn what we need to figure out.

[00:48:28]

How am I going to extend my life year by year? And what are these non-toxic therapies? Am I going to adopt so that I can maintain my similar burden and so I can slow down the epigenetic modification of my genes? I can keep more of them active before they get turned dormant because we don't know right now how to turn them back on after they've been turned off. But we can slow down that process right now. And we have regenerative techniques.

[00:48:56]

And whether it's with exosomes or stem cells or platelet rich plasma or peptides or a combination of all of them, we can repair broken tissues and then we can start to reverse biological age. And but for Horowitz, we didn't even know how to measure biological age. But now we have all of these different assays that can do thousands of metabolites and put them through an algorithm and say, here's a chronological age of fifty two and your biological age is a forty five or the other way around your chronological age is fifty two.

[00:49:31]

But now your biological age sixty two. Well that's not good, right. Well what can I do about that. And then we're seeing people in the clinic that have increased their, their average telomeres and we've seen people that have reduced their biologic or increased or reduced their biological age just by following protocols and supplements and peptides and whatnot.

[00:49:56]

So you've been able to test the the biological age of people. So for everyone, there's a chronological there's there's my birthdays at this time and this is how much how long I've been around. But then there's actually the expression of biology is like some people look like they're 40, but they look like they're 70. But also we can tell now with the with the work of Horowitz and things like that, where you can test the telomeres length and the telomerase expression of how much telomerase you have and blah, blah, blah, that either through the cell replicating is either increasing that rate of loss biologically or or the body's ability to have more telomerase available.

[00:50:43]

So the less shortening on the chromosomes anyway. So so you've been testing people before and after with the biological testing and you're seeing through some of their protocols, their biological age is actually starting to go down.

[00:50:58]

Yeah, I wish I could get it on everyone, but it's kind of expensive testing.

[00:51:03]

But the people that are able to afford a full age reversal protocol, we're incorporating those both the telomere testing and the epigenetic testing and we haven't really seen.

[00:51:17]

So there's when you measure telomeres, you can see what's average telomeres and then you can see this other test, which is what is the critically short telomeres and the critically short telomeres are more important than the average length, the critically short of what we can also influence more, because that's how your body's working day to day, because those are the cells that are getting turned over, mostly white blood cells.

[00:51:42]

And that's what we want to affect the most, because as we age, our immune system gets hammered and it's called immuno senescence. So if we can help the essence of the elderly, we're going to help them in all kinds of ways. And that slows down their aging and allows them to fight off viruses and fight off chronic disease. And if they were to get covid, they wouldn't have nearly the the problems that they could. We only have a sample of two in our clinic that have had covid over the age of 80.

[00:52:15]

But neither of those people had any effect. They had the virus, but they didn't feel ill or anything.

[00:52:23]

So because you were optimizing their their body systems and their immune system during the. Process, I would like to take full credit for that, and it's such a small number that like, you know, but but we have really good data just even with vitamin D that you can look there's so many good papers that have come out recently.

[00:52:45]

It's not a vitamin. It's a steroid hormone responsible for modulating over two hundred of your genes. The people that are over the age of 60 with less than twenty seven vitamin D are high risk for death. So, I mean, the simple thing we can do in the world and from functional medicine, from the research that we looked at is if you could just replace the vitamin D, get everyone on the planet and give them the algae oil that doko so ximo acid, you could probably get rid of 30, 30 percent of diseases on the planet.

[00:53:19]

Well, just those two things. Well, so but it's not it doesn't become mainstream and nobody really pushes. I mean, like people like us push it, but we're still in the great minority right now, unfortunately.

[00:53:34]

But we have to do it. And the people that are never going to be open to it and they listen to the mainstream and that's a whole rabbit hole that we could definitely uncork. But I think at the end of the day, there's so much responsibility that is a good thing that we should rely on ourselves for the optimization of our life and take it on as as as this is this is your body. This is your life. Be responsible for what you're doing with it and what you're putting in your mouth.

[00:54:13]

And and if the world is such a way that the American Medical Association is mostly a drug system, then we have to look towards the Passo Institute. We have to look for that because the proactivity is so vital for people like the what you're doing today is affecting your tomorrow. And and that goes for you or against you. So it's extremely important. And what goes in your mouth and what you do every day is is so vital. I mean, I love I mean, there's so many different places.

[00:54:57]

I feel like I can talk to you forever. What do you think? Just hitting on that note in a high level. What do you think right now as people are listening to this? A few top things people can do for their for anti aging, right? What are some what are your highlights of of helping people with my highlights for sure.

[00:55:24]

Start with a plant based diet. And when you when you begin a plant based diet, it's also a spiritual exercise. So I like to tell people that you need to work on your spirit. And that word is used a little bit too often, has been watered down. But if I told you that somebody had a really powerful spirit. And you didn't know anything else about them, you probably know how they're going to act in a lot of different situations, right?

[00:55:53]

If you tell that person something just happened to one of their loved ones, didn't lose it, or do they ask you pinpoint questions of where are they, what's going on and then take action? Right. Or if that person was insulted? Did they go off? Did they start crying? Or do they start yelling at the person or they just say whatever? Right. So you want to have a powerful spirit because you're not just you're not moved by all these things.

[00:56:17]

You're solid in what you want to do and you're focused. So how do you get that? And when you start doing something like a plant based diet, you're like, oh, well, well, I'm doing something for my environment, right? I'm doing something ethically because I don't want to take the life of that animal and I don't want that to suffer. And, well, I'm going to better myself, but I'm going to be healthier. I'll be able to live longer.

[00:56:40]

I have less chance of getting sick. So what's the downside? Well, there isn't any and I'm affecting my government in my world. And by pushing it towards the businesses that are going to be beneficial rather than the businesses that are not. So that's a spiritual exercise just in and of itself. And then you start building on what supplements do I need to take because I live in this world where I can't really get all the supplements I want. And one of the most important ones being vitamin D.

[00:57:08]

Well, I'm not a hunter gatherer and I don't live at the equator and I'm not naked running around eight to 10 miles a day. Right. So I need to take that supplement that would have been made. And I don't really want to look like a hunter gatherer that's been in the sun every day at the equator when I get older and have the risk of wrinkled skin and melanoma. So I'm going to take that vitamin D. So I would suggest that everyone take vitamin D, that they take DHEA.

[00:57:37]

I don't like fish oils are great and you can take all the officials you want. There's lots of data on there. If you can afford the algae oils, I like those better. They're better absorbed and you don't have to worry about how they're gathered and stuff like that. You don't need as much smaller capsules. So algae, oil and vitamin D, the first two supplements eat plant based and then have some practice that you're going to do that allows you to become very mindful of who you are and what you do.

[00:58:07]

So whether that's a yoga practice, whether that's Chigorin Tichy walking meditation, listen to Tick, not on the Buddhist monk. He'll tell you how to walk and meditate and then explosive activity. Get out there and do something that really stimulates your body to act a really strong stressor in a good way. Those are my top things.

[00:58:35]

That is, man, I'm excited. Just just for that. For that. The way you put that is so wonderful because. I believe it to my core about the spirit and I've been using this term about the science of you, meaning like us, we need to learn and cultivate who we are and allow that to come out and to be unique.

[00:59:02]

And and I love what you said. I agree 100 percent, man. I've just really enjoyed connecting. I love that we just kind of are meeting at this point because I feel like I feel like there's a lot of stuff. And I want to stay connected with you. I want to know what you're doing and the listeners will want to know what you're doing. So we'll put all of that information in the in the show notes. And let's just stay connected, dude.

[00:59:29]

And there's a lot of things I'd love to share and you can share with me. And we need we need this kind of light in the world. We need powerful, strong spiritual people saying that non religiously. But the spirit is strong. The spirit of strong people, let's say. But I appreciate your time immensely and I'm stoked that you're on the planet.

[00:59:58]

Now, we've reached a part of the show where we address society's fatal conveniences and how we can avoid falling into them and being a victim of them. I define fatal conveniences as the things we may be doing because the world we live in makes us believe we have to. And even though they may be saving us time or tricking us into thinking they're good for us, the truth is they're not. In fact, they could be slowly harming us and even killing us.

[01:00:35]

OK, everybody. Hey, how's it going? Very convenient time. This is going to be weird one. This is this this one might surprise you.

[01:00:44]

I think it might. So you know how the habit of going outside and putting on some sunglasses and the more you do it, the more that's a ritual and the more you do it, your eyes get sensitive and sensitive and sensitive and you keep putting your sunglasses on. Every time that there's even light outside these fatal convenience, his sunglasses may be causing depression, lack of sleep, circadian rhythm disturbances and even skin cancer. Yup, that's right. Wearing sunglasses.

[01:01:22]

The major thing is the conveniences is bright out, it's bright out. And you throw on sunglasses to try to keep the sun out of your eyes. And the more you do it, just like any muscle, the weaker your eyes get. We've never done that as a human species until, what, 50 years ago, if that. And so we're in this thing now where everyone's doing it, so now there's a lot of evidence showing that sunglasses might play a key role in depression.

[01:01:57]

So this was a study done by one, two, three, four, five top researchers out of the Middle East. And the hypothesis was that wearing sunglasses reduces the exposure of the eyes to sunlight and create what is a dim environment. So you put dark sunglasses on. It tricks the eyes thinking that it's still dark. Now, listen to this. This is common sense. You're going to start getting this. Wow, that makes sense. So then your body is tricked into thinking it doesn't have to fully wake up.

[01:02:39]

It doesn't have to create the serotonin and the hormones support and it and it thinks it's going to sleep again. So then it disrupts the melatonin production, the serotonin production, like I said, then responsible intimately to the circadian rhythm disruption.

[01:02:59]

So then you can't sleep. So it's a cascade effect that is mimicking what has been proven as winter depression, seasonal depressive disorders.

[01:03:11]

So wearing sunglasses is a mini version of that, reducing the sunlight exposure by wearing these sunglasses and causing a domino effect. There's a cool book out.

[01:03:25]

So the name of the book is Survival of the Sickest, where Dr. Sharon Mowlam, one of the things that she went into is the process of this sunglasses disrupting the ultraviolet light, the process of tanning and getting their body ready to produce melanin. But Dr. Molholm says sunglasses make the brain think it's dark. And this means you're not starting the natural process of tanning. You're more likely to burn, therefore, at more risk of skin cancer. Whoa.

[01:04:06]

What another researcher says he acknowledges that there were other factors that led to tanning and said light in the eye is an important factor. It helps to short circuit the body's natural defense mechanisms against the sun so it gets ready to prepare the skin. Dr Mohammed's theory is borne out of the research published in the Journal of Investigative Dermatology, suggesting that UV light in the eye activates a chemical known as melanocytes stimulating hormone that makes the skin thicken and go brown to protect it from harmful rays.

[01:04:54]

Professor John Hauk, melanoma expert for the British Skin Foundation, agreed. The production of the body's tanning tanning chemicals will almost certainly be diminished by sunglasses. Holy shit, everybody. What? Let me back up here. Let me back up.

[01:05:20]

The fatal convenience is you think your eyes are sensitive to sun? Well, you've programmed them and train them to be sensitive. So therefore you put sunglasses on. You don't allow the light to hit your pineal gland. You don't let that pineal gland tell your body in your your skin production to create melanin through melanocytes stimulating hormone. You can't tan effectively to protect yourself from the sun. Therefore, you're actually putting yourself at greater risk of skin cancer because your body thinks it's at night.

[01:05:56]

Then you add on top of it where the skin and the cholesterol are for the production of vitamin D. Everybody, now your immune system is compromised with not being able to produce the effect of vitamin D from the sun exposure. So now your entire immune system is governed by vitamin D, is affected your skin. Now, is that more danger? To not being able to produce the brown pigments to protect it from the sun exposure so that it can keep Garner garnering more and more vitamin D.

[01:06:37]

People don't wear sunglasses, not to mention their serotonin effect, the good feeling effect. So this is what I want you to do. This is what I want you to do. Let yourself practice. Let yourself get some sun exposure from your eyes for sure. The first 30 minutes of every day. Try to heat that new light that will reset your say in rhythm and you will sleep better. And when the sun goes down, but during the day practice, it hurts your eyes.

[01:07:09]

Then start with a few minutes and just keep going. I have never worn sunglasses in the last twenty five years. Not once, not once. Once you prepare your body to be natural, to not be fearful of the light, you will be liberated, you'll be healthier. Your skin, your immune system, your brain, your good mood, serotonin, anti depressant, all of that stuff. Common sense. People don't wear sunglasses. Today's fatal inconvenience throws sunglasses away.

[01:07:47]

All right. I love you all from the bottom of my heart.

[01:07:54]

That was a fantastic episode. What was the one thing that you got out of today's conversation? If today's episode struck a chord with you and you want to dive a little deeper, more episodes are available on Derren only Dotcom as well. Keep diving, my friends. Keep diving. This episode is produced by my team at Must Amplify, an audio marketing company that specializes in giving a voice to a brand and making sure the right people hear it.

[01:08:31]

If you would like or are thinking about doing a podcast or even would like a strategy session to add your voice to your brand in a powerful way.

[01:08:42]

Go to w w w dot must amplify dot com backslash, Daryn. That's w w w must amplify dot com backslash, Daryn.